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Amino Columns in Chromatography
Use of amino column in HPLC method development

bhaskar napte
Oct 20, 20231 min read
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Retention of Acidic, Basic, and Neutral Compounds in Ion Pair Chromatography
Retention of Acidic, Basic, and Neutral Compounds in Ion Pair Chromatography

bhaskar napte
Oct 20, 20233 min read
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Exploring the Surprising Increase in Retention Time of Protonated Bases at Low pH in RPLC
Exploring the Surprising Increase in Retention Time of Protonated Bases at Low pH in RPLC

bhaskar napte
Oct 20, 20232 min read
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UNDERSTAND OOS IN 10 MINUTES
Understand OOS procedure in 10 minutes

bhaskar napte
Oct 20, 20233 min read
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Why does Acetonitrile have higher elution strength than methanol?
We will explore, why Acetonitrile has higher elution strength than methanol.

bhaskar napte
Oct 20, 20232 min read
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Phenyl Column Mystery
The role of Phenyl column in HPLC method development

bhaskar napte
Oct 20, 20232 min read
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Unraveling the Advantages of Core-Shell Columns in HPLC
what core-shell particles are, how they differ from traditional porous particles, their history, and the advantages they bring

bhaskar napte
Oct 20, 20232 min read
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Methanol vs. Acetonitrile: Which Solvent is Better for Chromatography?
we'll explore the unique properties of methanol and acetonitrile and discuss when and why you might prefer one over the other for HPLC

bhaskar napte
Oct 20, 20232 min read
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Optimizing Your HPLC Performance: The Crucial Components You Shouldn't Overlook
We'll explore the often-overlooked components that can significantly impact your HPLC performance

bhaskar napte
Oct 20, 20232 min read
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QbD vs AQbD
Understanding the key terms associated with QbD (Quality by Design) and AQbD (Analytical Quality by Design)

bhaskar napte
Oct 20, 20232 min read
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Efficient Tips for Column Cleaning in Reverse Phase Liquid Chromatography
highly effective tips for column cleaning, particularly geared toward reverse-phase liquid chromatography

bhaskar napte
Oct 20, 20232 min read
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EMA's Latest Guidance on AI Limits of Nitrosamine
Introduction: Greetings! In a recent development, the European Medicines Agency (EMA) has made significant revisions to its Questions and...

bhaskar napte
Oct 20, 20235 min read
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Unveiling the Power of HILIC Columns in Liquid Chromatography
HILIC columns and the chemistry behind them.

bhaskar napte
Oct 20, 20233 min read
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The Crucial Role of Water in Normal Phase Liquid Chromatography
Introduction: Today we're going to dive into a fascinating topic in the world of liquid chromatography: the importance of adding water to...

bhaskar napte
Oct 20, 20233 min read
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Unlocking the Power of Hydrophilic Interaction Liquid Chromatography (HILIC)
Introduction Today, we're about to embark on a journey to discover the fascinating world of Hydrophilic Interaction Liquid...

bhaskar napte
Oct 20, 20233 min read
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Effect of Organic Solvents on the pKa of Ionizable Solutes in Reverse Phase Liquid Chromatography
Introduction: Greetings, I'm Bhaskar Napte from Pharma Growth Hub, and today we'll delve into an intriguing topic – the influence of...

bhaskar napte
Oct 20, 20233 min read
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